ATE12497T1 - Tricyclische aether, verfahren zu ihrer herstellung und ihre verwendung in heilmitteln. - Google Patents
Tricyclische aether, verfahren zu ihrer herstellung und ihre verwendung in heilmitteln.Info
- Publication number
- ATE12497T1 ATE12497T1 AT82401567T AT82401567T ATE12497T1 AT E12497 T1 ATE12497 T1 AT E12497T1 AT 82401567 T AT82401567 T AT 82401567T AT 82401567 T AT82401567 T AT 82401567T AT E12497 T1 ATE12497 T1 AT E12497T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- lower alkyl
- aethers
- tricyclic
- medicines
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- -1 pyrrolidino, piperidino Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/16—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D267/18—[b, e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Anesthesiology (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Luminescent Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8116347A FR2512024A1 (fr) | 1981-08-27 | 1981-08-27 | Ethers tricycliques, leur preparation et les compositions pharmaceutiques les contenant |
EP82401567A EP0074304B1 (fr) | 1981-08-27 | 1982-08-24 | Ethers tricycliques, leur préparation et les compositions pharmaceutiques les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE12497T1 true ATE12497T1 (de) | 1985-04-15 |
Family
ID=9261704
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT82401567T ATE12497T1 (de) | 1981-08-27 | 1982-08-24 | Tricyclische aether, verfahren zu ihrer herstellung und ihre verwendung in heilmitteln. |
Country Status (14)
Country | Link |
---|---|
US (1) | US4496557A (en]) |
EP (1) | EP0074304B1 (en]) |
JP (1) | JPS5874673A (en]) |
AT (1) | ATE12497T1 (en]) |
AU (1) | AU8773082A (en]) |
CA (1) | CA1227481A (en]) |
DE (1) | DE3262880D1 (en]) |
ES (1) | ES8400422A1 (en]) |
FR (1) | FR2512024A1 (en]) |
GR (1) | GR77595B (en]) |
IL (1) | IL66650A (en]) |
NZ (1) | NZ201740A (en]) |
PT (1) | PT75471B (en]) |
ZA (1) | ZA826252B (en]) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8500273D0 (sv) * | 1985-01-22 | 1985-01-22 | Leo Ab | Nya tricykliska foreningar, kompositioner innehallande sadana foreningar, framstellningsforfaranden och behandlingsmetoder |
EP0332246A1 (en) * | 1988-03-11 | 1989-09-13 | Akzo N.V. | Tricyclic amine derivatives |
US5180736A (en) * | 1989-03-23 | 1993-01-19 | Warner-Lambert Company | Polycyclic amines useful as cerebrovascular agents |
US5006536A (en) * | 1989-12-26 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals Inc. | Thienobenzoxepins and analgesic compositions thereof |
US5260319A (en) * | 1989-12-26 | 1993-11-09 | Hoechst-Roussel Pharmaceuticals Incorporated | Thienobenzoxepins and naphthothiophenes |
US5574173A (en) * | 1993-12-06 | 1996-11-12 | Schering Corporation | Tricyclic derivatives, compositions and methods of use |
ATE203528T1 (de) * | 1995-02-08 | 2001-08-15 | Novartis Erfind Verwalt Gmbh | Antineurodegenerativ wirksame 10-aminoaliphatyl- dibenz- b,f oxepine |
US5698551A (en) * | 1995-04-07 | 1997-12-16 | Novo Nordisk A/S | Heterocyclic compounds |
US8571289B2 (en) | 2002-11-27 | 2013-10-29 | Hologic, Inc. | System and method for generating a 2D image from a tomosynthesis data set |
US7577282B2 (en) | 2002-11-27 | 2009-08-18 | Hologic, Inc. | Image handling and display in X-ray mammography and tomosynthesis |
US7123684B2 (en) | 2002-11-27 | 2006-10-17 | Hologic, Inc. | Full field mammography with tissue exposure control, tomosynthesis, and dynamic field of view processing |
US8565372B2 (en) | 2003-11-26 | 2013-10-22 | Hologic, Inc | System and method for low dose tomosynthesis |
US7616801B2 (en) | 2002-11-27 | 2009-11-10 | Hologic, Inc. | Image handling and display in x-ray mammography and tomosynthesis |
US10638994B2 (en) | 2002-11-27 | 2020-05-05 | Hologic, Inc. | X-ray mammography with tomosynthesis |
US8768026B2 (en) | 2003-11-26 | 2014-07-01 | Hologic, Inc. | X-ray imaging with x-ray markers that provide adjunct information but preserve image quality |
US7662082B2 (en) | 2004-11-05 | 2010-02-16 | Theragenics Corporation | Expandable brachytherapy device |
EP2602743B1 (en) | 2004-11-15 | 2014-11-05 | Hologic, Inc. | Matching geometry generation and display of mammograms and tomosynthesis images |
EP3106094B1 (en) | 2004-11-26 | 2021-09-08 | Hologic, Inc. | Integrated multi-mode mammography/tomosynthesis x-ray system |
US7245694B2 (en) | 2005-08-15 | 2007-07-17 | Hologic, Inc. | X-ray mammography/tomosynthesis of patient's breast |
US8079946B2 (en) | 2005-11-18 | 2011-12-20 | Senorx, Inc. | Asymmetrical irradiation of a body cavity |
JP5554927B2 (ja) | 2006-02-15 | 2014-07-23 | ホロジック, インコーポレイテッド | トモシンセシスシステムを使用した乳房バイオプシおよびニードル位置特定 |
US7630533B2 (en) | 2007-09-20 | 2009-12-08 | Hologic, Inc. | Breast tomosynthesis with display of highlighted suspected calcifications |
US7991106B2 (en) * | 2008-08-29 | 2011-08-02 | Hologic, Inc. | Multi-mode tomosynthesis/mammography gain calibration and image correction using gain map information from selected projection angles |
CA2735935C (en) | 2008-09-04 | 2017-07-25 | Hologic Inc. | Integrated multi-mode mammography/tomosynthesis x-ray system and method |
US9579524B2 (en) | 2009-02-11 | 2017-02-28 | Hologic, Inc. | Flexible multi-lumen brachytherapy device |
US9248311B2 (en) | 2009-02-11 | 2016-02-02 | Hologic, Inc. | System and method for modifying a flexibility of a brachythereapy catheter |
US8170320B2 (en) * | 2009-03-03 | 2012-05-01 | Hologic, Inc. | Mammography/tomosynthesis systems and methods automatically deriving breast characteristics from breast x-ray images and automatically adjusting image processing parameters accordingly |
US10207126B2 (en) | 2009-05-11 | 2019-02-19 | Cytyc Corporation | Lumen visualization and identification system for multi-lumen balloon catheter |
EP2485651B1 (en) | 2009-10-08 | 2020-12-23 | Hologic, Inc. | Needle breast biopsy system |
US9352172B2 (en) | 2010-09-30 | 2016-05-31 | Hologic, Inc. | Using a guide member to facilitate brachytherapy device swap |
KR101836549B1 (ko) | 2010-10-05 | 2018-03-08 | 홀로직, 인크. | Ct 모드, 다중 단층영상합성 모드들, 및 유방조영술 모드를 갖는 직립형 x-레이 유방 촬영 |
WO2012071429A1 (en) | 2010-11-26 | 2012-05-31 | Hologic, Inc. | User interface for medical image review workstation |
US10342992B2 (en) | 2011-01-06 | 2019-07-09 | Hologic, Inc. | Orienting a brachytherapy applicator |
CA2829349C (en) | 2011-03-08 | 2021-02-09 | Hologic, Inc. | System and method for dual energy and/or contrast enhanced breast imaging for screening, diagnosis and biopsy |
US11259759B2 (en) | 2011-11-18 | 2022-03-01 | Hologic Inc. | X-ray mammography and/or breast tomosynthesis using a compression paddle |
EP2782505B1 (en) | 2011-11-27 | 2020-04-22 | Hologic, Inc. | System and method for generating a 2d image using mammography and/or tomosynthesis image data |
US9805507B2 (en) | 2012-02-13 | 2017-10-31 | Hologic, Inc | System and method for navigating a tomosynthesis stack using synthesized image data |
US10092358B2 (en) | 2013-03-15 | 2018-10-09 | Hologic, Inc. | Tomosynthesis-guided biopsy apparatus and method |
JP6392309B2 (ja) | 2013-03-15 | 2018-09-19 | ホロジック インコーポレイティッド | 自動合焦を含む、トモシンセシススタックをナビゲートするためのシステム |
ES2954561T3 (es) | 2013-10-09 | 2023-11-23 | Hologic Inc | Tomosíntesis de mama por rayos X que potencia la resolución espacial, incluso en la dirección de grosor de una mama aplanada |
CN106170255A (zh) | 2013-10-24 | 2016-11-30 | 安德鲁·P·史密斯 | 用于导航x射线引导的乳房活检的系统和方法 |
EP3110332B1 (en) | 2014-02-28 | 2018-04-11 | Hologic Inc. | System and method for generating and displaying tomosynthesis image slabs |
JP6749322B2 (ja) | 2014-11-07 | 2020-09-02 | ホロジック, インコーポレイテッドHologic, Inc. | マンモグラフィ/トモシンセシスx線システムのための枢動パドル装置 |
WO2017185028A1 (en) | 2016-04-22 | 2017-10-26 | Hologic, Inc. | Tomosynthesis with shifting focal spot x-ray system using an addressable array |
JP2019533510A (ja) | 2016-11-08 | 2019-11-21 | ホロジック, インコーポレイテッドHologic, Inc. | 湾曲した圧迫要素を用いた撮像 |
JP7174710B2 (ja) | 2017-03-30 | 2022-11-17 | ホロジック, インコーポレイテッド | 合成乳房組織画像を生成するための標的オブジェクト増強のためのシステムおよび方法 |
US11455754B2 (en) | 2017-03-30 | 2022-09-27 | Hologic, Inc. | System and method for synthesizing low-dimensional image data from high-dimensional image data using an object grid enhancement |
WO2018183548A1 (en) | 2017-03-30 | 2018-10-04 | Hologic, Inc. | System and method for hierarchical multi-level feature image synthesis and representation |
DE202018006897U1 (de) | 2017-06-20 | 2024-06-03 | Hologic Inc. | Dynamisches, selbstlernendes System für medizinische Bilder |
CA3069752A1 (en) | 2017-08-11 | 2019-02-14 | Hologic, Inc. | Breast compression paddle with access corners |
US11064956B2 (en) | 2017-08-11 | 2021-07-20 | Hologic, Inc. | Breast compression paddle having an inflatable jacket |
DE202018006917U1 (de) | 2017-08-16 | 2024-07-18 | Hologic Inc. | Techniken zur Patientenbewegungsartefaktkompensation bei Brustbildgebung |
EP3449835B1 (en) | 2017-08-22 | 2023-01-11 | Hologic, Inc. | Computed tomography system and method for imaging multiple anatomical targets |
US11090017B2 (en) | 2018-09-13 | 2021-08-17 | Hologic, Inc. | Generating synthesized projection images for 3D breast tomosynthesis or multi-mode x-ray breast imaging |
JP7441828B2 (ja) | 2018-09-24 | 2024-03-01 | ホロジック, インコーポレイテッド | 乳房マッピングおよび異常定位 |
AU2019346527B2 (en) | 2018-09-28 | 2025-03-06 | Hologic, Inc. | System and method for synthetic breast tissue image generation by high density element suppression |
WO2020107019A1 (en) | 2018-11-25 | 2020-05-28 | Hologic, Inc. | Multimodality hanging protocols |
WO2020205610A1 (en) | 2019-03-29 | 2020-10-08 | Hologic, Inc. | Snip-triggered digital image report generation |
EP3832689A3 (en) | 2019-12-05 | 2021-08-11 | Hologic, Inc. | Systems and methods for improved x-ray tube life |
KR20220130759A (ko) | 2020-01-24 | 2022-09-27 | 홀로직, 인크. | 수평-변위 가능 발포체 유방 압축 패들 |
US11471118B2 (en) | 2020-03-27 | 2022-10-18 | Hologic, Inc. | System and method for tracking x-ray tube focal spot position |
US11786191B2 (en) | 2021-05-17 | 2023-10-17 | Hologic, Inc. | Contrast-enhanced tomosynthesis with a copper filter |
US12186119B2 (en) | 2021-10-05 | 2025-01-07 | Hologic, Inc. | Interactive model interface for image selection in medical imaging systems |
US12254586B2 (en) | 2021-10-25 | 2025-03-18 | Hologic, Inc. | Auto-focus tool for multimodality image review |
AU2022398632A1 (en) | 2021-11-29 | 2024-07-11 | Hologic, Inc. | Systems and methods for correlating objects of interest |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3609167A (en) * | 1962-04-02 | 1971-09-28 | Smith Kline French Lab | IBENZO{8 b,e{9 {0 THIEPINES |
NL125253C (en]) * | 1963-12-05 | |||
NL152845B (nl) * | 1966-03-11 | 1977-04-15 | Boehringer Mannheim Gmbh | Werkwijze voor het bereiden van een geneesmiddel met een psychotrope en bloedsomloopstimulerende werking, alsmede het aldus verkregen gevormde geneesmiddel, en werkwijze voor het bereiden van een geneeskrachtig omega,omega-difenylalkylaminederivaat. |
FR1518226A (fr) * | 1966-04-09 | 1968-03-22 | Boehringer & Soehne Gmbh | Procédé pour la préparation de dérivés tricy cliques n-alcoylés de l'acétamide |
US4463001A (en) * | 1980-10-20 | 1984-07-31 | Farmitalia Carlo Erba S.P.A. | 6-Substituted 6H-dibenzo[b,d]pyran derivatives and process for their preparation |
-
1981
- 1981-08-27 FR FR8116347A patent/FR2512024A1/fr active Granted
-
1982
- 1982-08-16 US US06/408,451 patent/US4496557A/en not_active Expired - Fee Related
- 1982-08-20 CA CA000409886A patent/CA1227481A/fr not_active Expired
- 1982-08-24 AT AT82401567T patent/ATE12497T1/de active
- 1982-08-24 DE DE8282401567T patent/DE3262880D1/de not_active Expired
- 1982-08-24 EP EP82401567A patent/EP0074304B1/fr not_active Expired
- 1982-08-25 GR GR69103A patent/GR77595B/el unknown
- 1982-08-25 ES ES515232A patent/ES8400422A1/es not_active Expired
- 1982-08-26 IL IL66650A patent/IL66650A/xx unknown
- 1982-08-26 ZA ZA826252A patent/ZA826252B/xx unknown
- 1982-08-26 AU AU87730/82A patent/AU8773082A/en not_active Abandoned
- 1982-08-26 PT PT75471A patent/PT75471B/pt unknown
- 1982-08-26 JP JP57148452A patent/JPS5874673A/ja active Granted
- 1982-08-27 NZ NZ201740A patent/NZ201740A/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0074304B1 (fr) | 1985-04-03 |
PT75471A (fr) | 1982-09-01 |
ZA826252B (en) | 1983-07-27 |
IL66650A (en) | 1985-08-30 |
ES515232A0 (es) | 1983-11-01 |
EP0074304A1 (fr) | 1983-03-16 |
ES8400422A1 (es) | 1983-11-01 |
FR2512024B1 (en]) | 1984-01-06 |
NZ201740A (en) | 1985-05-31 |
PT75471B (fr) | 1984-11-19 |
CA1227481A (fr) | 1987-09-29 |
US4496557A (en) | 1985-01-29 |
IL66650A0 (en) | 1982-12-31 |
GR77595B (en]) | 1984-09-25 |
AU8773082A (en) | 1983-03-03 |
DE3262880D1 (en) | 1985-05-09 |
JPS6129950B2 (en]) | 1986-07-10 |
JPS5874673A (ja) | 1983-05-06 |
FR2512024A1 (fr) | 1983-03-04 |
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